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Metal Ion Interactions with mAbs: Part 2. Zinc-Mediated Aggregation of IgG1 Monoclonal Antibodies

Shrenik Mehta1, Heather Flores1, Benjamin Walters2

  • 1Pharmaceutical Development, Genentech, 1 DNA Way, South San Francisco, California, 94080, USA.

Pharmaceutical Research
|August 12, 2021
PubMed

Keywords:
IgG1 monoclonal antibodiesZn2+ mediated aggregationhigh molecular weight speciesisodesmic polymerization

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