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Updated: Oct 24, 2025

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Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
Published on: May 6, 2010
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Using Open Chromatin Enrichment and Network Hi-C (OCEAN-C) to Identify Open Chromatin Interactions
Lumeng Jia1, Cheng Li2, Tingting Li3
1Center for Bioinformatics, School of Life Sciences, Center for Statistical Science, Peking University, Beijing, China.
Methods in Molecular Biology (Clifton, N.J.)
|August 12, 2021
Abstract:
The open chromatin enrichment and network Hi-C (OCEAN-C) was developed not only for identifying large-scale chromatin structures, including topologically associated domains (TADs) and A/B compartments, but also for globally mapping hubs of open chromatin interactions (HOCIs) and their interaction networks independent of antibody and bait-sequences.

