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Physical quantities useful for quality control of quantitative SPECT/CT imaging
Sara Kurkowska1, Bożena Birkenfeld2, Hanna Piwowarska-Bilska2
1Department of Nuclear Medicine, Pomeranian Medical University, Szczecin, Poland. sarakurkowska95@gmail.com.
Nuclear Medicine Review. Central & Eastern Europe
|August 12, 2021
Summary
Standardizing calibration and quality control (QC) for quantitative SPECT/CT is crucial for reproducible results. This study proposes key parameters to assess quantitative SPECT/CT system and image quality, aiding nuclear medicine departments.
Area of Science:
- Nuclear Medicine
- Medical Imaging Physics
- Radiology
Background:
- Single-photon emission computed tomography/computed tomography (SPECT/CT) is evolving from qualitative to quantitative analysis.
- Quantitative SPECT/CT requires robust calibration, optimization, and quality control (QC) protocols.
- Lack of standardization in SPECT/CT calibration and QC hinders cross-center data exchange and reproducibility.
Purpose of the Study:
- To address the pressing need for standardization in quantitative SPECT/CT calibration and QC.
- To present key physical quantities for assessing quantitative SPECT/CT system and image quality.
- To support physicists in implementing quantitative SPECT/CT in clinical settings.
Main Methods:
- Evaluation of three physical quantities for quantitative SPECT/CT system characterization.
- Review and assessment of seven quantities used in the literature for quantitative SPECT/CT image quality.
- Utilized standard gamma camera QC software, external quantitative analysis programs, and clinical software.
Main Results:
- Identified critical parameters for quantitative SPECT/CT system performance evaluation.
- Provided a framework for assessing quantitative SPECT/CT image quality using established metrics.
- Demonstrated the necessity of integrated software solutions for comprehensive QC.
Conclusions:
- Standardization of calibration and QC is essential for advancing quantitative SPECT/CT.
- The proposed parameters offer a pathway towards reproducible and comparable quantitative SPECT/CT measurements.
- This work aims to facilitate the adoption and reliable implementation of quantitative SPECT/CT across nuclear medicine departments.
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