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Published on: February 6, 2019
Breast Cancer Treatment.
Kathryn P Trayes1, Sarah E H Cokenakes2
1Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Breast cancer risk can be assessed, with high-risk patients potentially benefiting from risk-reducing medications tailored to menopausal status. Treatment strategies for breast cancer are stage-dependent, ranging from surgery and radiation for early stages to systemic therapies for advanced or metastatic disease.
Area of Science:
- Oncology
- Women's Health
Background:
- Breast cancer is a leading global cause of cancer death in women.
- Risk assessment tools aid in identifying high-risk individuals for preventative measures.
- Treatment and management strategies are highly dependent on the stage of breast cancer.
Purpose of the Study:
- To outline breast cancer risk assessment and management.
- To detail treatment modalities based on cancer staging.
- To discuss therapeutic options for various stages of breast cancer, including ductal carcinoma in situ and metastatic disease.
Main Methods:
- Review of current breast cancer risk assessment tools.
- Description of treatment phases: preoperative, surgical, and postoperative.
- Categorization of treatment options by cancer stage and receptor status (ER, PR, ERBB2).
Main Results:
- Ductal carcinoma in situ (DCIS) treatment involves surgery and potentially endocrine therapy.
- Non-metastatic invasive breast cancers (Stages I-III) involve multi-phase treatment including systemic therapies, surgery (lumpectomy or mastectomy), and adjuvant treatments.
- Metastatic (Stage IV) breast cancer is manageable, focusing on improving quality and length of life.
Conclusions:
- Risk stratification is crucial for preventative interventions.
- A multi-modal, stage-specific approach is essential for effective breast cancer treatment.
- Ongoing research and tailored therapies offer improved outcomes for breast cancer patients.
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