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Updated: Oct 24, 2025

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
Main outcomes of M-bridge: A sequential multiple assignment randomized trial (SMART) for developing an adaptive
Megan E Patrick1, Grace R Lyden2, Nicole Morrell3
1Survey Research Center, Institute for Social Research, University of Michigan.
A universal adaptive preventive intervention (API) did not significantly reduce binge drinking among first-year students. However, resource emails were effective for heavy drinkers, and students joining Greek life benefited more from the API.
Area of Science:
- Public Health
- Psychology
- Intervention Science
Background:
- College students face significant alcohol-related risks during their transition.
- Adaptive Preventive Interventions (APIs) aim to mitigate these risks efficiently.
- A sequential multiple assignment randomized trial (SMART) design was employed to test intervention components.
Purpose of the Study:
- To evaluate the efficacy of an API compared to a control group for reducing first-year student binge drinking.
- To compare different intervention sequences within the API.
- To identify moderators of intervention effects, particularly for students at higher risk.
Main Methods:
- A SMART design with two randomizations: intervention timing and bridging strategy for heavy drinkers.
- Participants (N=891) received personalized normative feedback and self-monitoring.
- Outcomes measured included binge drinking frequency, alcohol consequences, and health services utilization.
Main Results:
- The overall API did not show significant effects compared to the control group.
- No significant differences were found between the embedded API variations.
- Heavy drinkers receiving a resource email showed increased health services utilization compared to those invited to health coaching.
- Students intending to join Greek life demonstrated a smaller increase in binge drinking with the API.
Conclusions:
- While the universal API lacked overall efficacy, targeted strategies show promise.
- Resource emails may be an effective, low-intensity intervention for heavy-drinking college students.
- Interventions may be more effective for specific subgroups, such as students entering Greek life.
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