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Directed Induction of Retinal Organoids from Human Pluripotent Stem Cells
Published on: April 21, 2021
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Transitioning into GMP-Compliance: Alternative Methods for Producing Retinal Organoids for Transplantation
Hannah Cobb1, Silvia Aparicio-Domingo1, M Valeria Canto-Soler1,2
1CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado, School of Medicine, Aurora, CO, USA.
Translational Vision Science & Technology
|August 12, 2021
Abstract
Translational Relevance:
Designing a GMP-compliant protocol for three-dimensional retinal organoid production is of urgent need in order to bring transplantation of hiPSC-derived retinal tissue and derived cells to clinical trials - and ultimately patient treatment - for retinal degenerative diseases.
