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Partial two-stage exchange: an alternative method for infected total hip arthroplasty
Mumingjiang Yishake1,2, Lan Tang2, Xi Chen2,3
1Department of Orthopedic Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang, Hangzhou, China.
BMC Musculoskeletal Disorders
|August 13, 2021
Summary
Partial two-stage exchange (PTE) is a viable treatment for infected total hip arthroplasty (THA), offering good infection control and functional outcomes with less harm than traditional methods.
Area of Science:
- Orthopedic Surgery
- Infectious Disease Management
- Arthroplasty Revision
Background:
- Total two-stage exchange (TSE) for infected total hip arthroplasty (THA) causes significant bone loss and trauma.
- Partial two-stage exchange (PTE) presents an alternative approach to managing infected THA.
Purpose of the Study:
- To evaluate the clinical outcomes of partial two-stage exchange (PTE) for infected total hip arthroplasty (THA).
- To compare the efficacy and safety of PTE against traditional TSE methods.
Main Methods:
- Retrospective analysis of 28 patients undergoing PTE for infected THA (September 2000 - June 2019).
- PTE involved preserving the femoral stem, replacing acetabular components with an antibiotic-loaded spacer, followed by reimplantation.
- Eligibility required a well-fixed femoral stem prosthesis.
Main Results:
- Overall success rate of 85.7% (24/28 patients) after an average follow-up of 4 years.
- Mean Harris hip score of 76.2 ± 11.7 at final follow-up.
- Demonstrated satisfactory infection control and functional recovery.
Conclusions:
- PTE is an acceptable option for select patients with infected THA.
- PTE achieves comparable infection control and clinical outcomes to TSE with reduced morbidity.
- PTE offers a less invasive alternative for managing infected THA.

