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Updated: Oct 24, 2025

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Primary Central Nervous System Leukemia Presenting as Altered Mental Status
1Department of Emergency Medicine, Indiana University, Indianapolis, Indiana.
Background:
Altered mental status is a common cause for presentation to the emergency department with a broad differential diagnosis.
Case Report:
We present a unique case of altered mental status in a previously healthy man that was found to be secondary to primary central nervous system acute lymphoblastic leukemia. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Lumbar puncture remains a critical tool for emergency physicians in the diagnosis of central nervous system pathologies.
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