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Updated: Oct 24, 2025

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Published on: January 22, 2018
Parathyroid Carcinoma - A Malignant Cause of Metabolic Skeletal Super Scan on Fluorodeoxyglucose Positron Emission
Santhosh Sampath1, Godwin Jeeva1
1Division of PET/CT, Gemini Scans, Chennai, Tamil Nadu, India.
Abstract:
Excessive abnormal tracer uptake in active tracer avid organ(s) with the suppression of physiological background tracer distribution is termed as super scan. Herein, we present an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT), where the metabolic pattern of skeletal super scan with coexistent parathyroid tumor was seen giving rise to the suspicion of primary hyperparathyroidism. It was subsequently diagnosed as a case of parathyroid carcinoma. Very high levels of serum parathormone in parathyroid carcinoma lead to accelerated bone turn over resulting in metabolic skeletal superscan in FDG-PET/CT which is seldom observed in parathyroid adenoma.
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