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COVID-19 induced bradyarrhythmia and relative bradycardia: An overview
Steven Douedi1, Anton Mararenko1, Abbas Alshami1
1Department of Internal Medicine Jersey Shore University Medical Center Neptune NJ USA.
Insights
COVID-19 can cause bradycardia (slow heart rate), affecting multiple organ systems. This review explores the epidemiology, pathogenesis, and management of bradyarrhythmia in COVID-19 patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- The novel coronavirus 2019 (COVID-19) pandemic has impacted global health significantly.
- While primarily a respiratory illness, COVID-19 affects multiple organ systems, including the cardiovascular system.
- Bradycardia is an emerging complication of COVID-19 with uncertain prognostic implications.
Purpose of the Study:
- To provide a comprehensive literature review on bradyarrhythmia in COVID-19 patients.
- To analyze the epidemiology, pathogenesis, and management strategies for COVID-19-induced bradyarrhythmia.
- To increase clinical awareness of cardiovascular manifestations of COVID-19.
Main Methods:
- Literature review of existing studies on COVID-19 and cardiovascular complications.
- Analysis of epidemiological data related to bradycardia in COVID-19.
- Synthesis of information on the pathogenesis and potential management of COVID-19-associated bradyarrhythmia.
Main Results:
- COVID-19 is associated with an increased incidence of various cardiovascular issues, including arrhythmias and cardiomyopathies.
- Bradycardia is a recognized, albeit not fully understood, complication of COVID-19.
- Existing cardiovascular disease increases mortality risk in COVID-19 patients.
Conclusions:
- COVID-19's impact on the cardiovascular system is extensive, necessitating clinical vigilance.
- Understanding the multifactorial pathogenesis of bradycardia in COVID-19 is crucial for patient management.
- Further research is needed to clarify the prognostic value and optimal treatment of bradyarrhythmia in COVID-19.
Abstract:
Novel coronavirus 2019 (COVID-19) has been the focus of the medical community since its emergence in December 2019 and has already infected more than 100 million patients globally. Primarily described to cause a respiratory illness, COVID-19 has been found to affect almost every organ system. Bradycardia is a newly recognized ramification of COVID-19 that still has unknown prognostic value. Studies have shown an increase in the incidence of arrhythmias, cardiomyopathies, myocarditis, acute coronary syndromes, and coagulopathies in infected patients as well as an increased risk of mortality in patients with preexisting cardiovascular disease. While the pathogenesis of bradycardia in COVID-19 may be multifactorial, clinicians should be aware of the mechanism by which COVID-19 affects the cardiovascular system and the medication side effects which are used in the treatment algorithm of this deadly virus. There has yet to be a comprehensive review analyzing bradyarrhythmia and relative bradycardia in COVID-19 infected patients. We aim to provide a literature review including the epidemiology, pathogenesis, and management of COVID-19 induced bradyarrhythmia.
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