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Traumatic Peripheral Nerve Injury in Mice
Published on: March 25, 2022
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Imaging of traumatic peripheral nerve injuries
Ankur Goyal1, Nagesh Wadgera1, Deep Narayan Srivastava1
1All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi, 110029, India.
Journal of Clinical Orthopaedics and Trauma
|August 13, 2021
Summary
Imaging, including high-resolution ultrasound (HUS) and magnetic resonance neurography (MRN), aids in grading peripheral nerve injuries. A proposed 3-tier imaging system helps assess nerve damage and recovery after trauma.
Area of Science:
- Orthopedics
- Radiology
- Neurology
Background:
- Peripheral nerve injuries from trauma significantly impact patients, necessitating prompt management decisions.
- Conventional assessment relies on clinical findings, patient progress, and electrophysiological studies.
- Imaging modalities are crucial for localizing, grading, and monitoring recovery of nerve injuries.
Purpose of the Study:
- To discuss imaging findings in various grades of peripheral nerve injury.
- To propose a simplified 3-tier grading system for imaging assessment of nerve injuries using HUS and MRN.
Main Methods:
- High-resolution ultrasound (HUS) is the primary imaging modality for peripheral nerves.
- Magnetic resonance neurography (MRN) complements HUS, particularly for muscle changes and deeper nerves.
- Correlation of imaging findings with different injury grades based on cross-sectional nerve layers.
Main Results:
- Imaging manifestations vary with nerve injury grade.
- HUS is optimal for peripheral nerve evaluation, while MRN offers complementary insights.
- Potential overlap in imaging findings exists due to limitations in detecting ultrastructural changes.
Conclusions:
- A 3-tier grading system for HUS and MRN can standardize peripheral nerve injury assessment.
- Imaging plays a vital role in guiding management and follow-up of nerve injuries.
- Accurate grading through imaging facilitates timely and effective treatment decisions.

