Jove
Visualize
Contact Us

Related Experiment Videos

Optimal perfusion during extra-corporeal circulation.

H M Koning1, A J Koning, J J Defauw

  • 1Department of Anesthesiology, St. Antonius Hospital, Nieuwegein/Utrecht, The Netherlands.

Scandinavian Journal of Thoracic and Cardiovascular Surgery
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

TENDL-based evaluation and adjustment of p+<sup>111</sup>Cd between 1 and 100 MeV.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2023
Same author

Evaluation of excitation functions of 100Mo(p,d+pn)99Mo and 100Mo (p,2n)99mTc reactions: Estimation of long-lived Tc-impurity and its implication on the specific activity of cyclotron-produced (99m)Tc.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2014
Same author

M1 gamma strength for zirconium nuclei in the photoneutron channel.

Physical review letters·2008
Same author

Light charged-particle production in 96 MeV neutron-induced reactions on carbon and oxygen.

Radiation protection dosimetry·2007
Same author

Nuclear theory for high-energy nuclear reactions of biomedical relevance.

Radiation protection dosimetry·2007
Same author

Partial photoneutron cross sections for the isomeric state 180Tam.

Physical review letters·2006
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Cardiac surgery patients need higher cardiopulmonary bypass blood flow with increased age and pre-operative creatinine to protect kidney function. A nomogram helps determine optimal blood flow to maintain postoperative serum creatinine levels.

Area of Science:

  • Nephrology
  • Cardiology
  • Surgical Research

Background:

  • Cardiac surgery can impact renal function.
  • Cardiopulmonary bypass (CPB) is a critical component of cardiac surgery.
  • Understanding factors influencing renal response is vital for patient outcomes.

Purpose of the Study:

  • To analyze the impact of age and CPB blood flow on renal function after cardiac surgery.
  • To identify key predictors of postoperative serum creatinine levels.
  • To develop a tool for optimizing CPB blood flow to preserve renal function.

Main Methods:

  • Multivariate analysis of 130 consecutive cardiac surgery patients.
  • Assessment of patient age, pre-operative serum creatinine, and CPB blood flow.
  • Correlation of these variables with postoperative serum creatinine levels.

Related Experiment Videos

Main Results:

  • Postoperative serum creatinine is significantly influenced by pre-operative creatinine, age, and lowest CPB blood flow.
  • Older patients and those with higher pre-operative creatinine require increased CPB blood flow.
  • A nomogram was developed to guide CPB blood flow adjustments.

Conclusions:

  • Optimizing CPB blood flow based on patient age and pre-operative renal function is crucial for preventing postoperative kidney injury.
  • The provided nomogram serves as a practical tool for clinicians.
  • Maintaining adequate blood flow during CPB is essential for renal protection in cardiac surgery.