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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Diagnostic and Management Considerations in Pediatric Dermatofibrosarcoma Protuberans.

Daniel J Reilly¹, Yew Loong Loo¹, William M Alexander¹

¹From the Department of Plastic and Maxillofacial Surgery, Royal Children's Hospital.

Annals of Plastic Surgery

|August 13, 2021

Summary

Pediatric dermatofibrosarcoma protuberans (DFSP) is rare. Surgical excision achieved recurrence-free survival in all pediatric patients, highlighting the importance of complete tumor removal.

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Area of Science:

Oncology
Pediatric Oncology
Dermatopathology

Background:

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing fibrohistiocytic tumor originating in the dermis.
Pediatric cases account for 6% of all DFSP diagnoses, with an incidence of 1 per million children.

Purpose of the Study:

To review the management and outcomes of pediatric dermatofibrosarcoma protuberans (DFSP) cases.
To evaluate the efficacy of surgical excision in achieving recurrence-free survival for pediatric DFSP.

Main Methods:

Retrospective review of pediatric DFSP cases managed at a single institution over 23 years.
Analysis of patient demographics, treatment modalities, and follow-up data.
Surgical excision as the primary treatment approach for all patients.

Main Results:

Seventeen pediatric patients (10 male, mean age 9.9 years) were included.
Median follow-up was 29 months, with no observed recurrences.
Complete surgical excision with clear margins (R0 resection) was achieved in all cases, with some requiring re-excision.

Conclusions:

Pediatric DFSP can be effectively managed with surgical excision, leading to excellent outcomes.
Multidisciplinary team management involving soft tissue tumor specialists, pathologists, and surgeons is crucial.
Achieving R0 resection is key to ensuring recurrence-free survival in pediatric DFSP.