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Related Experiment Video

Updated: Oct 24, 2025

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Hemispheric stroke: Mood disorders.

Michał Harciarek¹, Aleksandra Mańkowska¹

¹Department of Social Sciences, Institute of Psychology, University of Gdansk, Gdansk, Poland.

Handbook of Clinical Neurology

|August 14, 2021

Summary

Stroke survivors frequently experience mood disorders like depression, influenced by brain injury location. Understanding these emotional changes is key to recovery.

Area of Science:

Neuroscience
Psychiatry
Neurology

Background:

Stroke is a leading cause of disability.
Mood and emotional disorders are common post-stroke complications, affecting up to one-third of patients.
These disorders include depression, mania, anxiety, and apathy.

Purpose of the Study:

To discuss mood disorders associated with hemispheric strokes.
To explore the neuropsychological mechanisms underlying these affective disorders.

Main Methods:

Review of literature on stroke-related mood disorders.
Analysis of the relationship between brain injury characteristics (severity, side, hemisphere) and emotional outcomes.

Main Results:

Keywords:

Anosodiaphoria Apathy Mood disorders Poststroke depression Secondary mania

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Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Gathering Self-Initiated Rat Behavioral Data to Characterize Post-Stroke Deficits

Published on: March 15, 2024

Left hemispheric strokes are often linked to depression and anxiety.

Right hemispheric strokes are predominantly associated with emotional indifference or euphoria.

Mood disorder development depends on injury severity and location.

Conclusions:

Hemispheric location significantly influences the type of mood disorder post-stroke.
Neuropsychological mechanisms are crucial for understanding post-stroke affective changes.