Related Experiment Video

Updated: Oct 24, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.2K

Clinical Patterns and Risk Factors for Pneumonia Caused by Atypical Bacteria in Vietnamese Children

Phan Le Thanh Huong1, Pham Thu Hien2, Nguyen Thi Phong Lan1

  • 1National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.

Indian Pediatrics
|August 14, 2021
PubMed

Insights

Identifying atypical community-acquired pneumonia (CAP) in children is crucial. Clinical features and risk factors like age and asthma history help pinpoint children at higher risk for this infection.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Respiratory Medicine

Background:

  • Community-acquired pneumonia (CAP) is a common childhood illness.
  • Atypical pathogens cause a significant proportion of CAP cases.
  • Distinguishing typical from atypical CAP is important for appropriate management.

Purpose of the Study:

  • To investigate the clinical characteristics of atypical CAP in children.
  • To identify risk factors associated with atypical CAP in pediatric patients.

Main Methods:

  • Multiplex polymerase chain reaction and specific IgM were used to detect atypical bacteria.
  • 661 hospitalized children (aged 1-15 years) with CAP were analyzed.
  • Clinical and epidemiological data were compared between typical and atypical CAP groups.

Main Results:

  • Atypical CAP cases showed lower rates of wheezing and interstitial pneumonia.
  • Higher rates of asthma history, headache, chest pain, and lobar pneumonia were observed in atypical CAP.
  • Significant risk factors included age, season, asthma history, symptom duration, and radiological findings.

Conclusions:

  • Clinical characteristics and identified risk factors aid in identifying children with atypical CAP.
  • Early identification can facilitate timely and targeted treatment for pediatric CAP.
Abstract

More Related Videos

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness12:21

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

2.7K
Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/4306:06

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43

Published on: September 11, 2020

1.9K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
425
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.8K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
533
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
1.1K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
519
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
2.1K