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Updated: Oct 24, 2025

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve repair for endocarditis
Silvia Solari1, Emiliano Navarra1, Laurent de Kerchove1
1Cardiovascular and Thoracic Surgery Department, Saint Luc University Clinic, Brussels, Belgium.
Abstract:
Many authors have reported their results of mitral valve (MV) repair (MVr) in acute and healed endocarditis. However, the results published by different authors highlight the fact that the reparability rate for this indication remains low. Over the last three decades, our group has adopted an early and repair-oriented approach to infective endocarditis with the objective to improve the repair rate and the long-term results. In this paper, we describe our institutional experience on mitral valve repair for infective endocarditis. Data for this paper were extracted from our institutional database on heart valve disease. From 1991 to 2015, 160 consecutive patients in our institution underwent MV surgery for active IE on native MV. The median follow-up was 122 months. This study was approved by the institutional ethics review board, and written informed consent was waived for this study given its retrospective design. Hospital mortality was 11.6% (n = 18). Early MV reoperation before hospital discharge was required in five (3.1%) patients. At 5, 10, and 15 years, overall survival in the MVr for endocarditis in the group was 79% ± 4%, 65% ± 5%, 57% ± 6%, respectively. Freedom from reoperation at 5, 10, and 15 years was 95% ± 2%, 88% ± 4%, and 81% ± 6%, respectively. Mitral infective endocarditis is an insidious pathology and his surgical approach can be challenging. An early and repair-oriented surgical approach can allow to improve reparability rates with good long-term durability and a low recurrence rate of endocarditis.
Insights
An early, repair-focused surgical approach improves mitral valve repair rates for infective endocarditis. This strategy offers good long-term durability and low recurrence, enhancing patient outcomes in complex cases.
Area of Science:
- Cardiology
- Cardiac Surgery
- Infectious Diseases
Background:
- Mitral valve repair (MVr) in infective endocarditis (IE) has historically low reparability rates.
- Infective endocarditis presents challenges in surgical management due to its insidious nature.
Purpose of the Study:
- To describe institutional experience with mitral valve repair for infective endocarditis.
- To evaluate the efficacy of an early and repair-oriented surgical approach for IE.
- To assess long-term outcomes of mitral valve repair in patients with infective endocarditis.
Main Methods:
- Retrospective analysis of 160 consecutive patients undergoing mitral valve surgery for active IE on native MV from 1991 to 2015.
- Data extracted from an institutional heart valve disease database.
- Median follow-up of 122 months.
Main Results:
- Hospital mortality was 11.6%. Early reoperation was required in 3.1% of patients.
- Overall survival at 5, 10, and 15 years was 79%, 65%, and 57%, respectively.
- Freedom from reoperation at 5, 10, and 15 years was 95%, 88%, and 81%, respectively.
Conclusions:
- An early and repair-oriented surgical strategy can improve mitral valve repair rates in infective endocarditis.
- This approach demonstrates good long-term durability and a low recurrence rate of endocarditis.
- Mitral valve repair for infective endocarditis is feasible and yields favorable long-term results with appropriate surgical timing and technique.
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