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Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...

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Related Experiment Video

Updated: Oct 24, 2025

Author Spotlight: Development of a Scaffold-Free Acoustic Assembly Method for High-Quality 3D Cell Spheroid Culture

Author Spotlight: Development of a Scaffold-Free Acoustic Assembly Method for High-Quality 3D Cell Spheroid Culture

Published on: October 13, 2023

Surface acoustic wave (SAW) techniques in tissue engineering.

Deming Jiang¹, Jingwen Liu², Yuxiang Pan¹

¹Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, China.

Cell and Tissue Research

|August 14, 2021

Summary

This summary is machine-generated.

Surface acoustic wave (SAW) technology offers a non-invasive method for precise cell patterning in tissue engineering. This technique enables accurate cell sorting, manipulation, and rapid spheroid formation, advancing lab-on-a-chip systems.

Keywords:

Acoustic-wave sensors and actuators Bioengineering Biomedicine Microfluidics Surface acoustic wave Tissue engineering

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Last Updated: Oct 24, 2025

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Area of Science:

Biotechnology
Bioengineering
Microfluidics

Background:

Cellular communication is vital for tissue homeostasis, regeneration, and disease progression.
Traditional tissue engineering methods face challenges in cell patterning, being time-consuming and heterogeneous.
Effective cell patterning without compromising cell viability is crucial for tissue repair.

Purpose of the Study:

To review the application of Surface Acoustic Wave (SAW) technology in tissue engineering.
To highlight SAW as a biocompatible, label-free, and non-invasive tool for cell manipulation.
To introduce the concept of tissue engineering lab-on-a-chip systems using SAW devices.

Main Methods:

Utilizing Surface Acoustic Wave (SAW) devices for microfluidic applications.
Employing SAW technique for cell sorting, manipulation, and patterning.
Integrating multiple SAW devices onto lab-on-a-chip platforms.

Main Results:

SAW technique allows for accurate and non-invasive cell sorting and manipulation.
The method facilitates rapid formation of cell spheroids.
Integration of SAW devices enables the development of tissue engineering lab-on-a-chip systems.

Conclusions:

Surface Acoustic Wave (SAW) technology presents a promising solution for advanced cell patterning in tissue engineering.
SAW offers a biocompatible, label-free, and non-invasive approach, overcoming limitations of traditional methods.
This review highlights the novelty and potential of SAW in developing sophisticated tissue engineering platforms.