Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

390
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
390
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

1.1K
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
1.1K
Administering Oxygen by Mask01:30

Administering Oxygen by Mask

993
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
993
Oxygen Delivering System I: Nasal Cannula and Face Mask01:26

Oxygen Delivering System I: Nasal Cannula and Face Mask

786
The human body requires oxygen to function, and when the natural process of respiration is hindered, external devices, including the following, are needed to help deliver this vital gas.
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
786
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

1.3K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.3K
Administering Oxygen by Nasal Cannula01:29

Administering Oxygen by Nasal Cannula

1.3K
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations.
Nasal Cannulas
A nasal cannula is a lightweight tube split into two prongs placed in the nostrils,...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An oral glucose tolerance test does not affect cerebral blood flow: role of NOS.

American journal of physiology. Regulatory, integrative and comparative physiology·2023
Same author

Multimodality Deep Phenotyping Methods to Assess Mechanisms of Poor Right Ventricular-Pulmonary Artery Coupling.

Function (Oxford, England)·2022
Same author

Increased RV:LV ratio on chest CT-angiogram in COVID-19 is a marker of adverse outcomes.

The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology·2022
Same author

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest V<sub>E</sub> /VCO<sub>2</sub> and ETCO<sub>2</sub> identify pulmonary vascular disease.

Clinical cardiology·2022
Same author

Interferon-β-Induced Pulmonary Arterial Hypertension: Approach to Diagnosis and Clinical Monitoring.

JACC. Case reports·2021
Same author

The Use of Alveolar Dead Space Fraction to Predict Postoperative Outcomes after Pediatric Cardiac Surgery: A Retrospective Study.

Pediatric cardiology·2021

Related Experiment Video

Updated: Oct 24, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

8.4K

Decrease in dysbaric osteonecrosis severity as a result of 45-minute oxygen pre-breathe.

Jacob Lamers1,2, Kent MacLaughlin1,2, Dave Pegelow1,2

  • 1Department of Pediatrics, Division of Critical Care, University of Wisconsin School of Medicine and Public Health Madison, Wisconsin U.S.

Undersea & Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc
|August 14, 2021
PubMed
Summary

Forty-five minutes of oxygen (O2) pre-breathe is the minimum duration required to effectively reduce dysbaric osteonecrosis (DON) risk during disabled submarine escape (DISSUB). Shorter durations did not provide sufficient protection against bone necrosis from rapid decompression.

Keywords:
DISSUBdecompressiondysbaricosteonecrosis

More Related Videos

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

2.7K
A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

9.0K

Related Experiment Videos

Last Updated: Oct 24, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

8.4K
Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

2.7K
A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

9.0K

Area of Science:

  • Physiology
  • Baromedical Research
  • Toxicology

Background:

  • Sudden decompression during disabled submarine escape (DISSUB) can cause nitrogen (N2) bubble formation.
  • This bubble formation may lead to dysbaric osteonecrosis (DON), characterized by ischemia and necrosis in long bone marrow.
  • Previous studies indicated a two-hour oxygen (O2) pre-breathe reduces DON, but shorter durations are not well understood.

Purpose of the Study:

  • To investigate the efficacy of shorter oxygen (O2) pre-breathe durations in preventing dysbaric osteonecrosis (DON).
  • To determine the minimum effective O2 pre-breathe time for mitigating DON during simulated DISSUB at 33 fsw.

Main Methods:

  • Eight Suffolk ewes were exposed to 33 fsw for 24 hours, followed by rapid decompression.
  • Animals were randomly assigned to four groups: no O2 pre-breathe (control), or 15, 30, or 45 minutes of 91-88% O2 pre-breathe.
  • Alizarin complexone was administered to visualize and quantify DON in long bones.

Main Results:

  • The 15- and 30-minute O2 pre-breathe groups exhibited the greatest DON deposition.
  • The 45-minute O2 pre-breathe group showed a significant decrease in variance compared to all other groups.
  • A minimum of 45 minutes of O2 pre-breathe was necessary to effectively prevent DON at 33 fsw.

Conclusions:

  • Forty-five minutes of oxygen (O2) pre-breathe is the minimum duration required to significantly reduce dysbaric osteonecrosis (DON) risk during disabled submarine escape (DISSUB) at 33 fsw.
  • Shorter pre-breathe durations (15 and 30 minutes) were less effective and showed higher DON deposition.
  • Further research is needed to establish optimal O2 pre-breathe dosages for various DISSUB scenarios.