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Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro
Assaf Assis1, Yechiel N Gellman2, Avivit Cahn3
1Department of Cell and Developmental Biology, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.
Journal of Diabetes and Its Complications
|August 15, 2021
Abstract:
Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.

