Acute mesenteric arterial thrombosis in severe SARS-Co-2 patient: A case report and literature review

Montserrat Del Carmen Valencia Romero1, Adrián Morales Cárdenas2, Alberto Briseño Fuentes3

  • 1Resident of General Surgery, Hospital Civil Dr. Juan I. Menchaca, Mexico.

Abstract

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause intestinal thrombosis, leading to increased mortality. This complication, though rare, significantly elevates the risk of death in affected patients.

Area of Science:

  • Internal Medicine
  • Gastroenterology
  • Infectious Diseases

Background:

  • Coronavirus disease 2019 (COVID-19) infection induces a pro-inflammatory state, promoting thrombosis across various organ systems.
  • Multi-organ dysfunction is a significant cause of mortality in COVID-19.
  • Mesenteric ischemia is a reported complication in 1.9-4% of COVID-19 patients.

Observation:

  • A case report details a 73-year-old male with severe SARS-CoV-2 infection and arterial-type intestinal ischemia.
  • The patient experienced necrosis of 3 meters of small intestine, managed according to the SCARE 2020 guidelines.

Findings:

  • Thrombotic complications of SARS-CoV-2 include myocardial infarction (1.1%), ischemic cerebral events (2.5-3.7%), and microvascular thrombosis.
  • Mesenteric ischemia, a form of microvascular thrombosis, occurs in less than 1% of cases.
  • Postoperative mortality for mesenteric ischemia patients is high at 23.8%, particularly within the first 30 days.

Implications:

  • Intestinal thrombosis in COVID-19 patients is associated with increased mortality.
  • Early recognition and management of mesenteric ischemia in SARS-CoV-2 patients are crucial for improving outcomes.
  • Further research is needed to understand the mechanisms and optimize treatment strategies for COVID-19-associated thrombosis.

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