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Updated: Oct 24, 2025

Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
Perioperative Coagulation Monitoring
1Department of Anaesthesiology, Aarhus University Hospital, Palle Juul Jensens Boulevard, Aarhus N DK-8200, Denmark.
Perioperative coagulation monitoring enhances patient safety during surgery. This review discusses limitations of standard tests and the role of point-of-care devices in managing hemostatic dysfunctions.
Area of Science:
- Anesthesiology
- Hematology
- Surgical Sciences
Background:
- Perioperative bleeding and hemostatic challenges impact patient safety.
- Traditional coagulation tests have limitations in detecting complex hemostatic dysfunctions.
- Hyperfibrinolysis is particularly difficult to diagnose with standard methods.
Purpose of the Study:
- To review key issues and pathophysiologic changes affecting the perioperative hemostatic system.
- To evaluate the clinical utility of preoperative coagulation tests.
- To discuss the principles and application of point-of-care coagulation devices.
Main Methods:
- Literature review of perioperative coagulation.
- Discussion of pathophysiologic changes in hemostasis.
- Evaluation of standard and point-of-care coagulation testing.
Main Results:
- Standard coagulation tests are insufficient for comprehensive perioperative hemostasis assessment.
- Point-of-care devices, including platelet analyzers, offer valuable real-time data.
- Understanding pathophysiologic changes is crucial for effective monitoring.
Conclusions:
- Improved perioperative coagulation monitoring is essential for patient safety.
- Point-of-care testing provides a valuable adjunct to traditional methods.
- Further research into advanced monitoring techniques is warranted.
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