Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ectopic pregnancy and a sensitive test for urinary human chorionic gonadotropin.

L Frost1, J Møller

  • 1Department of Obstetrics and Gynecology, University Hospital of Aarhus, Denmark.

Acta Obstetricia Et Gynecologica Scandinavica
|January 1, 1987
PubMed
Summary

A highly sensitive human chorionic gonadotropin test effectively screens for ectopic pregnancy. This diagnostic tool demonstrated 100% specificity and 90% negative predictive value in 120 patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CYP2D6-inhibiting drugs and risk of fall injury after newly initiated therapy with beta-blockers-a register-based case-crossover study.

Scientific reports·2025
Same author

Trends in intentional and unintentional poisonings among older adults - A national register-based study in Sweden.

BMC geriatrics·2023
Same author

Environmental assessment of landfill gas mitigation using biocover and gas collection with energy utilisation at aging landfills.

Waste management (New York, N.Y.)·2023
Same author

Performance of a cryo-cooled crystal monochromator illuminated by hard X-rays with MHz repetition rate at the European X-ray Free-Electron Laser.

Optics express·2022
Same author

Pump-probe X-ray holographic imaging of laser-induced cavitation bubbles with femtosecond FEL pulses.

Nature communications·2021
Same author

Materials Imaging and Dynamics (MID) instrument at the European X-ray Free-Electron Laser Facility.

Journal of synchrotron radiation·2021

Area of Science:

  • Reproductive Endocrinology
  • Clinical Diagnostics
  • Obstetrics and Gynecology

Background:

  • Ectopic pregnancy poses a significant risk to maternal health.
  • Early and accurate diagnosis is crucial for effective management.
  • Human chorionic gonadotropin (hCG) is a key biomarker for pregnancy.

Purpose of the Study:

  • To evaluate the diagnostic performance of a commercially available, highly sensitive hCG test for routine screening of ectopic pregnancy.
  • To determine the sensitivity, specificity, and predictive values of the hCG test in patients with suspected ectopic pregnancy.

Main Methods:

  • A highly sensitive human chorionic gonadotropin (hCG) test with a detection threshold of 75 mIU/ml was implemented in daily clinical routine.
  • The test was prospectively applied to screen 120 patients diagnosed with ectopic pregnancy.

Related Experiment Videos

Main Results:

  • The hCG test achieved a diagnostic specificity of 100% in identifying ectopic pregnancies.
  • Sensitivity for detecting ectopic pregnancy was 96.7%.
  • The predictive value of a positive test was 100%, and a negative test was 90%.

Conclusions:

  • The highly sensitive hCG test is a valuable and accurate tool for the routine screening of ectopic pregnancy.
  • The test's high specificity and positive predictive value ensure reliable identification of ectopic pregnancies.
  • The diagnostic performance supports its use in early detection and management of ectopic pregnancy.