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A review on corona virus and treatment approaches with Allium sativam
Rupesh Kumar Pandey1, Ravindra Kumar Pandey2, Shiv Shankar Shukla2
1Department of Pharmacology KSCP, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh India.
Insights
Traditional herbal medicines, like garlic (Allium sativum), offer potential therapeutic strategies against emerging viral diseases such as Covid-19. Research explores garlic
Area of Science:
- Phytochemistry and Pharmacology
- Infectious Diseases
- Drug Discovery
Background:
- Emerging infectious diseases, exemplified by Covid-19, highlight the urgent need for novel therapeutic interventions.
- The global health crisis necessitates exploring alternative and traditional medicine systems for disease management.
- Limited treatment options for new viral pathogens underscore the importance of investigating natural compounds.
Purpose of the Study:
- To investigate the potential of traditional herbal medicines, specifically garlic (Allium sativum), as a therapeutic agent against Covid-19.
- To elucidate the mechanism of action of garlic constituents against the SARS-CoV-2 virus.
- To explore the role of traditional herbs in addressing novel diseases where modern medicine is lacking.
Main Methods:
- Review of scientific literature on the antiviral properties of Allium sativum.
- Analysis of the structural components of the SARS-CoV-2 virus and potential drug targets.
- Conceptualization of garlic's mechanism of action against viral infections based on its chemical constituents.
Main Results:
- Identification of key chemical constituents in Allium sativum with potential therapeutic benefits.
- Elucidation of allicin as a significant compound in garlic with targeted therapeutic sites relevant to Covid-19.
- Demonstration of garlic's potential as a complementary or alternative treatment strategy.
Conclusions:
- Allium sativum, particularly its constituent allicin, presents a promising avenue for Covid-19 drug discovery.
- Traditional herbal medicines can serve as valuable resources for developing treatments against novel viral diseases.
- Further research into phytocompounds is crucial for combating future pandemics.
Background:
Recently reported cases of Covid-19 globally remind us that new diseases are coming while we are unable to provide the treatment for the same. The entire world is facing this viral attack; deaths are increasing day by day as well as infected patients too. Today, in the period of this disease, can we go to the shelter of our traditional medicines?
Main Body:
In this article, we have taken medicines related to corona and conceptualized their mechanism, which gave us a chance to understand Garlic's mechanism of action, how Garlic can be a weapon in the lane with this disease. This article also tells how we can treat new diseases with our traditional herbs if no modern medicine has been discovered yet.
Conclusion:
The present review is based on the structure of the virus and the targeted site for the drug discovery process with important constituents of Allium sativam. The review work also explains the allicin chemical constituent of Allium sativam which has targeted therapeutic sites related to Covid-19.
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