Related Experiment Video
Updated: Oct 24, 2025
Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
Published on: June 20, 2014
Myocarditis following mRNA vaccination against SARS-CoV-2, a case series
William W King1, Matthew R Petersen1, Ralph M Matar2
1Department of Internal Medicine, University of Florida, 1600 SW Archer Road, Room 4102, Gainesville, FL 32610-0277, United States of America.
Introduction:
mRNA COVID-19 vaccines have emerged as a new form of vaccination that has proven to be highly safe and effective against COVID-19 vaccination. Rare adverse events including myocarditis have been reported in the literature.
Methods:
Data were gathered from the electronic medical record of four patients personally treated by the authors.
Results:
Four patients, ages 20 to 30, presented with myocarditis characterized by chest pain, elevations in troponin-I and C-reactive protein, and negative viral serologies two to four days following mRNA vaccine administration. One had a cardiac MRI showing delayed gadolinium enhancement in a subpericardial pattern. All experienced symptom resolution by the following day, and the two who have returned for follow-up had normal troponin-I and CRP values.
Discussion:
Along with previously reported instances, these cases raise suspicion for a possible link between mRNA vaccines and myocarditis.
