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Updated: Oct 24, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive sleep apnea and injury events in Taiwanese adults: A retrospective cohort study
Chia-Ling Lin1, Mei-Chen Su2, Chun-Ping Lin3
1Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan, R.O.C.
Purpose:
The aim of this study was to examine the association between obstructive sleep apnea (OSA) diagnosis and diverse types of injuries.
Design:
This population-based retrospective cohort study compared records from 2000 to 2013 in the Taiwan National Health Insurance Research Database.
Methods:
3025 patients identified with OSA were compared against the control cohort consisting of 12,100 age- and sex-matched patients. Cox proportional hazards regression analysis was performed to estimate the effects of OSA on injury risk.
Findings:
Patients with OSA exhibited a significantly higher overall incidence of injury of 2599 per 100,000 person-years compared to the control cohort (2248 per 100,000 person-years). After the confounding factors were considered, subjects with OSA showed a higher risk of injury than subjects in the control group (adjusted hazard ratio [HR] = 1.78, 95% confidence interval [CI] = 1.64-1.93). The risk of unintentional injury (traffic, poisoning, falls) and intentional injury (suicide) in the group of patients with OSA was higher than that in the controls.
Conclusions:
Our study strongly supports the conclusion that adults with OSA are at increased risk of injury.
Clinical Relevance:
The present results indicate the significance of OSA as a predictor of injury risk, which will provide valuable information for clinical practice and injury prevention.
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