Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

390
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
390
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

492
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
492
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

1.1K
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
1.1K
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

243
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
243
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

206
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
206
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

289
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
289

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the Effectiveness of Nonpharmacological Self-Management Interventions for Persistent Pain: Protocol for Single-Case Experimental Designs.

JMIR research protocols·2026
Same author

Jumping in: Research skills development in general practice training, and incentives, barriers and enablers for novice GP researcher journeys.

Australian journal of general practice·2026
Same author

De/Medicalisation is not the problem: On the idea of a "law clinic" for people experiencing housing instability and homelessness.

Health (London, England : 1997)·2026
Same author

Deprescribing in Older People: A Clinical Practice Guideline Summary.

The Medical journal of Australia·2026
Same author

Christian religion and spirituality in eating disorder development, experience, and recovery: an exploration of lived experience in Australia and New Zealand.

Frontiers in psychology·2026
Same author

Use of electronic point-of-care resources by early-career general practitioners and associations with their use during consultations: A cross-sectional analysis of consultation data.

BMJ open·2025

Related Experiment Video

Updated: Oct 24, 2025

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

21.7K

Heliox for croup in children.

Irene Moraa1, Nancy Sturman2, Treasure M McGuire1,3,4

  • 1School of Pharmacy, The University of Queensland, Brisbane, Australia.

The Cochrane Database of Systematic Reviews
|August 16, 2021
PubMed
Summary
This summary is machine-generated.

Helium-oxygen (heliox) therapy may offer short-term benefits for moderate croup but lacks sufficient evidence for mild or severe cases. More research is needed to confirm heliox

More Related Videos

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

2.9K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.8K

Related Experiment Videos

Last Updated: Oct 24, 2025

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
04:46

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation

Published on: January 17, 2011

21.7K
Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

2.9K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.8K

Area of Science:

  • Pediatric Emergency Medicine
  • Respiratory Medicine
  • Critical Care

Background:

  • Croup is a common viral respiratory infection in children, causing upper airway inflammation and potential respiratory distress.
  • Standard treatments like corticosteroids and nebulized epinephrine have limitations, including delayed or short-lived effects and potential adverse events.
  • Helium-oxygen (heliox) is an inhaled gas mixture explored for its potential to reduce airway resistance and improve respiratory distress in croup.

Purpose of the Study:

  • To evaluate the effectiveness of heliox compared to oxygen, placebo, or other interventions in relieving croup symptoms in children.
  • To assess heliox's impact on croup scores, hospital admission rates, and intubation rates.
  • To update previous reviews on heliox for croup treatment.

Main Methods:

  • Systematic review and meta-analysis of randomized controlled trials (RCTs) and quasi-RCTs.
  • Searched multiple databases (CENTRAL, MEDLINE, Embase, etc.) and clinical trial registries up to April 2021.
  • Included 3 RCTs with 91 children (6 months to 4 years) comparing heliox with oxygen or no treatment.

Main Results:

  • Heliox showed no significant difference compared to 30% humidified oxygen for mild croup.
  • In moderate croup treated with dexamethasone, heliox may offer short-term improvement in croup scores and respiratory rate.
  • Evidence quality was low across studies due to imprecision, risk of bias, and limited reporting on adverse events and hospitalizations.

Conclusions:

  • The effectiveness and safety of heliox for croup remain uncertain due to limited evidence.
  • Heliox may provide transient benefits for moderate croup but is not definitively superior to standard treatments.
  • Further large-scale, high-quality RCTs are required to establish heliox's role in managing pediatric croup.