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The application value of operating room ventilation with laminar airflow for surgical site infection: A protocol for
Yuan-Yuan Liu1, Ling-Yun Shi2, Yong-Mei Duan3
1Department of Operating Room Disinfection Supply Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Background:
The presence of biological particles in the air inside operating theatres has the potential to cause severe surgical site infections. Recently, laminar airflow systems have been regarded as a means to reducing surgical site infections using airborne microbes. Still, other publications have argued the benefits of laminar airflow systems, stating the likelihood of adverse effects. Therefore, we will conduct this systematic study to evaluate the applicational value of adopting laminar airflow systems in operating theatres to minimize surgical site infections.
Methods:
Reporting of this study adheres to the guidelines of Preferred Reporting Items for Systematic Review and Meta-analysis Protocols. The authors will perform a systematic search on MEDLINE, Web of Science, EMBASE, the China national knowledge infrastructure, and the Cochrane Library from their commencement until June 2021. The search will identify relevant randomized and non-randomized controlled trials that evaluates the applicational value of using laminar airflow ventilation in surgical theatres to minimize surgical site infections. There are no restrictions on language. Two authors will independently screen the identified studies, perform data extraction, and use an appropriate method to evaluate the bias risk in the included studies.
Results:
The work done in the present study will enhance the existing literature on the applicational value of laminar airflow ventilation in surgical theatre to reduce surgical site infections.
Conclusion:
The outcomes are a reference for healthcare practitioners and patients when making informed decisions regarding care during surgeries.
Insights
This systematic review evaluates laminar airflow systems for reducing surgical site infections. The findings will guide healthcare professionals and patients in making informed decisions about operating theatre ventilation strategies.
Area of Science:
- Healthcare Engineering
- Infection Control
- Environmental Health
Background:
- Airborne biological particles in operating theatres pose a risk for surgical site infections.
- Laminar airflow systems are proposed to mitigate airborne microbes, but their efficacy is debated.
- Contradictory findings necessitate a comprehensive evaluation of laminar airflow systems in surgical settings.
Purpose of the Study:
- To systematically assess the value of laminar airflow systems in operating theatres.
- To determine the effectiveness of laminar airflow ventilation in minimizing surgical site infections.
- To provide evidence-based recommendations for the adoption of these systems.
Main Methods:
- Systematic literature search across major databases (MEDLINE, Web of Science, EMBASE, CNKI, Cochrane Library) until June 2021.
- Inclusion of randomized and non-randomized controlled trials evaluating laminar airflow ventilation in surgical theatres.
- Independent study screening, data extraction, and bias risk assessment by two authors.
Main Results:
- This study will synthesize current evidence on the application of laminar airflow ventilation in operating theatres.
- The findings will clarify the impact of laminar airflow systems on reducing surgical site infections.
- The research aims to enhance the existing body of literature on this topic.
Conclusions:
- The study outcomes will serve as a crucial reference for healthcare practitioners and patients.
- Informed decisions regarding surgical care and operating theatre environments can be made based on the findings.
- Evidence-based guidance on the use of laminar airflow systems will be provided.

