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Pulmonary mucinous cystadenoma complicated with infection: A rare case report
Zhou-Ye Luo1, Xun-Ze Shen1, Fang Liu2
1PET/CT Center, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, Zhejiang Province, China.
Rationale:
Mucinous cystadenoma is a benign tumor that is commonly found in the pancreas, ovaries, or appendix, but is rarely encountered in the lungs. Worldwide, only a few reported cases of these tumors originate in the lungs. Herein, we analyzed the imaging features of a case of pulmonary mucinous cystadenoma (PMCA). To the best of our knowledge, this is the first reported case of PMCA complicated by significant infection.
Patient Concerns:
A 57-year-old man was admitted to our hospital with blood in sputum for more than 2 months. Serum laboratory examination showed significantly elevated leukocyte and tumor marker, carcinoembryonic antigen. Enhanced thoracic computed tomography and whole-body positron emission tomography/computed tomography showed a cystic-solid ill-defined mass in the right upper lung.
Diagnosis:
The tumor was considered malignant, both clinically and radiologically.
Interventions:
The patient underwent right upper lobe tumor resection and mediastinal lymph node dissection.
Outcomes:
Postoperative specimen pathology was diagnosed as PMCA with infection. The patient was not administered any further treatment. The patient was alive without any recurrence or metastasis of the tumor after 2 years of follow-up.
Lessons:
Preoperative diagnosis of PMCA with atypical imaging and clinical manifestations is extremely difficult. This is the first reported case of PMCA complicated by a significant infection that was misdiagnosed preoperatively as a malignancy.
Insights
Pulmonary mucinous cystadenoma (PMCA) is rare, especially when complicated by infection. This case highlights diagnostic challenges, with imaging initially suggesting malignancy despite the benign tumor.
Area of Science:
- Pulmonary Medicine
- Oncology
- Radiology
Background:
- Pulmonary mucinous cystadenoma (PMCA) is an exceptionally rare lung tumor, with few documented cases globally.
- This report details a unique case of PMCA complicated by significant infection, a presentation not previously described.
Observation:
- A 57-year-old male presented with hemoptysis, elevated leukocytes, and carcinoembryonic antigen.
- Imaging revealed a cystic-solid mass in the right upper lung, raising suspicion for malignancy.
- The patient underwent surgical resection of the right upper lobe tumor.
Findings:
- Postoperative pathology confirmed PMCA with superimposed infection.
- The patient received no further treatment and showed no recurrence after a 2-year follow-up.
Implications:
- Preoperative diagnosis of PMCA is challenging due to atypical imaging and clinical features.
- This case underscores the difficulty in differentiating infected PMCA from lung malignancy based on initial assessments.
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