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Updated: Oct 24, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Current devices and interventions in mitral regurgitation.
Benedikt Koell1,2, Daniel Kalbacher1,2, Edith Lubos3,4,5
1Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany.
Transcatheter mitral regurgitation (MR) therapies offer alternatives to surgery for aging patients. This review explores evolving interventional treatments for MR, including edge-to-edge repair and valve implantation.
Area of Science:
- Cardiology
- Interventional Cardiology
- Valvular Heart Disease
Background:
- Mitral regurgitation (MR) is the most common valvular heart disease, with increasing prevalence in aging populations.
- High surgical risk in elderly patients with comorbidities drives the need for less invasive treatments.
- Transcatheter therapies are emerging as crucial alternatives to drug or surgical interventions for MR.
Purpose of the Study:
- To review the current landscape of transcatheter therapies for mitral regurgitation.
- To highlight the evolution and expanding options for interventional MR treatment.
- To discuss patient-oriented therapeutic strategies for diverse MR pathologies.
Main Methods:
- Review of current literature on transcatheter mitral regurgitation therapies.
- Discussion of established and emerging interventional techniques.
- Analysis of treatment options for primary and secondary MR.
Main Results:
- Transcatheter mitral valve repair (e.g., edge-to-edge repair) is a well-established treatment.
- Direct/indirect annuloplasty and transcatheter mitral valve implantation are expanding treatment options.
- A broad spectrum of interventional therapies allows for individualized patient treatment.
Conclusions:
- Transcatheter therapies are increasingly important for managing mitral regurgitation in high-risk patients.
- The evolving armamentarium of interventional procedures provides tailored solutions for MR.
- Interventional cardiology offers patient-centered approaches to address various MR pathologies.
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