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Published on: December 6, 2016
Positional device therapy for the treatment of positional obstructive sleep apnea in children: a pilot study
Lena Xiao1, Adele Baker2, Giorge Voutsas1
1Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.
Insights
Positional obstructive sleep apnea (POSA) in children can be effectively treated with a positional device, a non-invasive therapy that prevents supine sleeping. This treatment offers a promising alternative for children who cannot tolerate continuous positive airway pressure.
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Medicine
- Biomedical Engineering
Background:
- Obstructive sleep apnea (OSA) in children poses a challenge, especially for those intolerant to continuous positive airway pressure (CPAP).
- Positional OSA (POSA), where OSA predominantly occurs in the supine position, is a common phenotype.
- Effective interventions for POSA in children are lacking, highlighting a critical research gap.
Purpose of the Study:
- To evaluate the efficacy of a positional device as a treatment for POSA in children.
- To assess the impact of positional therapy on the obstructive apnea-hypopnea index (OAHI) in pediatric patients.
Main Methods:
- An observational study involving children aged 4-18 years diagnosed with POSA.
- Baseline polysomnography (PSG) followed by a second PSG while using a positional device.
- Primary outcome measured was the change in OAHI.
Main Results:
- Positional device therapy significantly reduced the median OAHI from 15.2 to 6.7 events/hour (p=0.004).
- The percentage of total sleep time in the supine position decreased significantly from 54.4% to 4.2% (p=0.04).
- Improvements in oxygen desaturation index were observed but not statistically significant.
Conclusions:
- Positional device therapy is an effective treatment for POSA in children.
- This therapy presents a potential cost-efficient and non-invasive clinical option for managing pediatric POSA.
Background:
There is a critical gap in identifying effective interventions for children with obstructive sleep apnea (OSA) who do not tolerate continuous positive airway pressure therapy. Positional OSA (POSA) is a common clinical phenotype whereby OSA occurs predominantly while sleeping in supine position. POSA may be amenable to treatment with a positional device, a belt worn around the chest with cushions on the back to prevent supine positioning, but no data exists in children. The primary aim of this study was to evaluate the efficacy of positional device therapy for the treatment of POSA in children.
Methods:
This observational study included children aged 4-18 years with POSA and an obstructive apnea-hypopnea index (OAHI) ≥ 5 events/hour on baseline polysomnogram (PSG) who underwent a second PSG to evaluate the efficacy of a positional device. The primary outcome was the change in OAHI.
Results:
Ten children were included (8 male, median age 11.2 years, median body mass index z-score 1.6). Compared to the baseline PSG, PSG data obtained while using a positional device showed a reduced median (interquartile range) OAHI (15.2 [8.3-25.6] versus 6.7 [1.0-13.7] events/hour respectively; p = 0.004) and percentage of total sleep time in supine position (54.4 [35.0-80.6]% versus 4.2 [1.1-25.2]% respectively; p = 0.04). Despite observed improvements in the oxygen desaturation index, these results were not statistically significant.
Significance And Conclusions:
In this novel pilot study, positional device therapy was effective for the treatment of POSA. Positional device therapy may potentially change clinical practice as a cost-efficient and non-invasive treatment option for POSA.
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