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Updated: Oct 23, 2025

Metacarpal Small Incision for Carpal Tunnel Syndrome
Published on: April 5, 2024
Palmaris profundus in the carpal tunnel
Theodore Paul Pezas1, Rajive Jose2
1St George's University Hospital, St George's University Hospitals NHS Foundation Trust, London, UK.
Carpal tunnel release surgery can be complicated by the palmaris profundus, a rare anatomical variant. Awareness of this variant is crucial to prevent accidental median nerve damage during carpal tunnel decompression.
Area of Science:
- Anatomy
- Orthopedic Surgery
- Neurology
Background:
- Carpal tunnel release is a common surgical procedure to alleviate median nerve compression.
- Idiopathic causes are most frequent, but secondary causes are also recognized.
- Median nerve compression can lead to carpal tunnel syndrome (CTS).
Observation:
- The palmaris profundus is a rare anatomical variant distinct from the palmaris longus tendon.
- This variant courses under the flexor retinaculum, potentially reducing carpal tunnel space.
- Cases report close association between palmaris profundus and the median nerve within the carpal tunnel.
Findings:
- The palmaris profundus can act as a secondary cause of median nerve compression.
- Its anatomical course may contribute to or cause carpal tunnel syndrome.
- Intimate association with the median nerve is frequently observed in affected individuals.
Implications:
- Increased awareness of the palmaris profundus is vital for surgeons performing carpal tunnel decompression.
- Recognition can help prevent iatrogenic injury to the median nerve.
- Understanding this anatomical variant improves surgical outcomes and patient safety.
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