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Related Concept Videos

Penis01:29

Penis

12.0K
The penis serves a dual role in sexual reproduction and urination. It consists of three main regions: the glans penis, the body, and the root, each with distinct functions and unique anatomical features.
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
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Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

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Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
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Related Experiment Video

Updated: Oct 23, 2025

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
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Glans penis augmentation: when, how, and why?

Gianluigi Califano1, Davide Arcaniolo2, Claudia Collà Ruvolo1

  • 1Urology Unit, Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.

International Journal of Impotence Research
|August 17, 2021
PubMed
Summary
This summary is machine-generated.

Glans penis augmentation (GPA) offers solutions for cosmetic and functional concerns, but requires careful patient counseling and surgical expertise. Further research is needed to confirm long-term safety and effectiveness.

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Area of Science:

  • Andrological Surgery
  • Urology
  • Cosmetic Surgery

Background:

  • Glans penis augmentation (GPA) is increasingly requested but remains controversial due to limited evidence and technical challenges.
  • It addresses both aesthetic and functional concerns related to the glans penis.

Purpose of the Study:

  • To provide a comprehensive literature review on glans penis augmentation (GPA).
  • To offer an accessible overview of current GPA techniques and applications.

Main Methods:

  • Systematic review of existing literature on glans penis augmentation.
  • Analysis of treatment strategies, outcomes, and limitations.

Main Results:

  • GPA can manage glans-shaft asymmetries, size reduction, and loss of tumescence using fillers or surgery.
  • Injectable fillers show particular benefit for lifelong premature ejaculation.
  • Current studies are limited by small sample sizes and non-randomized designs, with poor complication reporting.

Conclusions:

  • Glans penis augmentation (GPA) requires thorough patient counseling and a deep understanding of glans anatomy.
  • Long-term efficacy and safety data for GPA techniques require further investigation.