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Multidetector Computed Tomography Findings of Acute Abdominal Intussusception Due to Peutz-Jeghers Syndrome

Hong Duc Pham1,2, Thai Hoa T Nguyen3, Thi Quynh Tran2

  • 1Radiology, Hanoi Medical University, Ha Noi, VNM.

Cureus
|August 17, 2021
PubMed

Insights

Peutz-Jeghers syndrome (PJS) can first present as bowel obstruction due to intussusception. This case highlights the diagnostic challenges and the role of MDCT in identifying PJS complications.

Area of Science:

  • Gastroenterology
  • Medical Genetics

Background:

  • Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder.
  • Characterized by hamartomatous polyps and mucocutaneous pigmentation.
  • Common complications include bleeding and bowel obstruction.

Observation:

  • A 17-year-old male presented with symptoms suggestive of PJS.
  • Initial diagnosis was delayed despite PJS traits.
  • Developed bowel obstruction secondary to ileo-ileal intussusception.

Findings:

  • Multidetector computed tomography (MDCT) revealed characteristic intussusception signs ('target' and 'pseudo-kidney').
  • MDCT identified a lead-point polyp as the cause.
  • Postoperative histopathology confirmed hamartoma, confirming PJS.

Implications:

  • Intussusception on MDCT is a critical indicator for PJS diagnosis.
  • Early diagnosis of PJS is crucial for managing complications.
  • Highlights the importance of considering PJS in young patients with intussusception.

Keywords:
image findingsintussusceptionmultidetector computed tomographypeutz-jeghers syndromesmall bowel obstruction

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