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Updated: Oct 23, 2025

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Idiopathic eosinophilic pleurisy: A practical diagnostic approach
Tetsuro Haraguchi1, Hiroki Tashiro1, Koichiro Takahashi1
1Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University Hospital, Saga, Japan.
Idiopathic eosinophilic pleurisy, characterized by eosinophils in pleural fluid and blood, can resolve with corticosteroid treatment. This case highlights a practical diagnostic approach for this rare condition.
Area of Science:
- Pulmonology
- Hematology
- Pathology
Background:
- Eosinophilic pleural effusion is a rare condition with diverse etiologies.
- Idiopathic eosinophilic pleurisy lacks an identifiable cause after thorough investigation.
Observation:
- A 37-year-old male presented with fever, cough, and dyspnea, developing eosinophilic pleural effusion and blood eosinophilia.
- Malignancy, infections, and myeloproliferative disorders were excluded through comprehensive investigations.
Findings:
- Thoracoscopy revealed eosinophilic infiltration in the pleura without necrosis or malignant cells.
- The patient was diagnosed with idiopathic eosinophilic pleurisy.
Implications:
- Corticosteroid therapy led to the resolution of eosinophilic pleural effusion.
- A systematic clinical approach is essential for investigating and diagnosing eosinophilic pleurisy, considering its varied etiologies.
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