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Updated: Oct 23, 2025
Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Comparison of RNC Coupling and CO Coupling Mediated by Cr-Cr Quintuple Bond and B-B Multiple Bonds: Main Group
Sagar Ghorai1, Raghavendra Meena1, Anju P Joseph1
1Inorganic and Physical Chemistry Department, Indian Institute of Science, Bangalore-560012, India.
Abstract:
A theoretical analysis of reductive coupling of isocyanide and CO mediated by a Cr-Cr quintuple bonded complex and B-B multiple bonded complexes shows how the difference in donor-acceptor capability of isocyanide and CO ligands controls the product distributions. In the case of CO, the Cr-Cr quintuple bonded complex is unable to show C-C coupling due to the high π- back bonding possibility of CO and the reaction follows the singlet potential energy surface throughout, whereas, in the case of isocyanide, less π- back bonding possibility allows the reactions to undergo a spin transition and gives a series of products with different spin multiplicities. Similarly, reactions of B-B multiple bonded complexes with CO and isocyanides are also controlled by donor-acceptor capabilities of ligands, and the C-C coupling takes place by changing the oxidation state of the boron centers from +I to +II, in contrast to the classical main group mediated reactions where stable oxidation states are always preserved. This part of the main group chemistry which is dominated by donor-acceptor bonding interaction is more likely to follow transition metal behavior.
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