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Antibiotic prescribing patterns for childhood infections in ambulatory settings in Jordan

Samah F Al-Shatnawi1, Sanabil Y Al-Hosban2, Shoroq M Altawalbeh1

  • 1Department of Clinical Pharmacy, Faculty of Pharmacy, University of Science and Technology, Irbid, Jordan.

International Journal of Clinical Practice
|August 17, 2021
PubMed

Insights

This study found high rates of antibiotic use in Jordanian pediatric outpatients, highlighting the need for better drug prescribing practices. Rational antibiotic use is crucial to combat antimicrobial resistance.

Area of Science:

  • Pharmacology and Pharmacy
  • Public Health
  • Pediatrics

Background:

  • Antimicrobial resistance is a global health threat, necessitating rational antibiotic prescribing.
  • The World Health Organization (WHO) emphasizes stewardship interventions to combat resistance.
  • Understanding prescribing patterns is vital for developing effective interventions, particularly in low-income settings.

Purpose of the Study:

  • To analyze pediatric antibiotic prescribing patterns in ambulatory settings in Jordan.
  • To provide data for guiding local antibiotic stewardship interventions.
  • To contribute to the global effort against antimicrobial resistance.

Main Methods:

  • A retrospective, cross-sectional study of 20,494 prescriptions for pediatric outpatients (≤18 years) in 2018.
  • Utilized the WHO's drug utilization model and analyzed prescribing indicators.
  • Employed multiple linear regression to identify factors influencing antibiotic prescription ratios.

Main Results:

  • Antimicrobials constituted 77.5% of all ambulatory prescriptions.
  • Antibiotics were most frequently prescribed for respiratory tract infections.
  • Age, gender, season, and facility type significantly predicted the ratio of antibiotics to total medications.

Conclusions:

  • This is the first comprehensive study on pediatric outpatient antibiotic prescribing in Jordan.
  • Results reveal high antibiotic utilization rates among pediatric outpatients.
  • Findings underscore the need for targeted regulations and focused efforts to promote rational drug use.
Abstract

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