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Published on: March 13, 2011
Ancestry analysis using autosomal SNPs in northern South America, reveals interpretation differences between an AIM
Dayana Suárez1, Raquel Cruz2, María Torres3
1Populations Genetics and Identification Group, Institute of Genetics, National University of Colombia, Bogotá, Colombia.
Abstract:
Current human populations are studied to elucidate their ancestry composition and to obtain reference values for an array of genetic markers for forensic practice. This study compared the 79 ancestry informative markers (AIMs) panel with the SNPforID 52plex set used in forensic identification, using samples belonging to Continental Caribbean populations from Colombia with a high percentage of locals self-determined as Native American descendants. The results show a bias in the individual estimation made with the identification markers, which disregards the Native American ancestry component and overestimates the African ancestry component. Also, the analysis made with the Bayesian Classification Algorithm shows better likelihoods for individual assignment with AIMs than with SNPforID 52plex.
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