Related Experiment Video

Updated: Oct 23, 2025

Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications
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Endotracheal Intubation via Tracheotomy and Subsequent Thoracotomy in Rats for Non-Survival Applications

Published on: March 15, 2024

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Survival and decannulation across indications for infant tracheostomy: a twelve-year single-center cohort study

Laura Sillers1, Janet Lioy2, Kevin Moran3

  • 1Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. sillersl@chop.edu.

Journal of Perinatology : Official Journal of the California Perinatal Association
|August 18, 2021
PubMed

Insights

Infant tracheostomy outcomes, including survival and decannulation, significantly vary based on the initial reason for the procedure. Neurologic or musculoskeletal indications predict lower decannulation rates in children.

Area of Science:

  • Pediatric Surgery
  • Respiratory Medicine
  • Neonatology

Background:

  • Infant tracheostomy is a critical intervention for various respiratory and airway issues.
  • Understanding post-tracheostomy outcomes is essential for optimizing patient care and parental counseling.

Purpose of the Study:

  • To analyze survival and decannulation rates in infants following tracheostomy.
  • To determine how these outcomes differ based on the primary indication for tracheostomy placement.

Main Methods:

  • Retrospective cohort study of 378 infants undergoing tracheostomy over 12 years.
  • Indications categorized into pulmonary, anatomic, cardiac, neurologic/musculoskeletal, and others.
  • Analysis of survival and decannulation data, including multivariable predictors.

Main Results:

  • Overall mortality was 26.3%, with significant differences in mortality across indications.
  • 69.3% of survivors were decannulated by a median age of 3.0 years.
  • Neurologic/musculoskeletal indications were associated with significantly lower decannulation rates (aOR 0.10).

Conclusions:

  • Early childhood outcomes after infant tracheostomy are highly dependent on the underlying indication.
  • Specific indications, particularly neurologic/musculoskeletal conditions, are linked to poorer decannulation prognosis.
Abstract

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