Cardiovascular injuries and SARS-COV-2 infection: focus on elderly people

Claudia Colombo1, Laura Garatti1,2, Giulia Ferrante3

  • 1Department of Cardiology De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Insights

This review examines the significant impact of COVID-19 on the cardiovascular system, particularly in elderly patients. It highlights increased risks due to comorbidities and discusses supportive treatments for severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) infection.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Geriatrics

Background:

  • COVID-19 poses a severe global health threat, with elderly individuals and those with comorbidities facing higher risks of mortality.
  • Cardiovascular complications, including myocardial injury and thromboembolism, are prevalent in COVID-19 patients.
  • Biomarkers like troponin, NTproBNP, and D-Dimer indicate disease severity and prognosis.

Purpose of the Study:

  • To review the complex interplay between COVID-19 and the cardiovascular system in the elderly population.
  • To explore supportive treatments for COVID-19 in older adults.
  • To address concerns related to comorbidities and polypharmacotherapy in this demographic.

Main Methods:

  • Literature review focusing on COVID-19, cardiovascular disease, and the elderly.
  • Analysis of prognostic biomarkers and their significance.
  • Examination of current supportive care strategies and challenges.

Main Results:

  • Elderly patients with comorbidities exhibit elevated risks of severe COVID-19 and cardiovascular complications.
  • Specific biomarkers are crucial for assessing prognosis in COVID-19 cases.
  • Management of COVID-19 in the elderly requires careful consideration of existing conditions and medications.

Conclusions:

  • COVID-19 significantly impacts the cardiovascular health of the elderly, exacerbating risks associated with pre-existing conditions.
  • Effective management necessitates a comprehensive approach addressing both viral infection and cardiovascular sequelae.
  • Further research into tailored supportive therapies is essential for improving outcomes in this vulnerable population.

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