[Comparison of premorbid personality and psychopathological structure of some anxiety-affective disorders]

To compare premorbid personality and structure of psychopathological status of organic anxiety-depressive disorder in comparison with endogenous depression and anxiety neurotic disorders.

One hundred and twelve patients, including 57 with organic anxiety-depressive disorder (OADD), 41 with endogenous depression (ED) and 14 with anxiety neurotic disorder (AND) were studied. have been included into the study. The Munich personality test (MPT) and Toronto alexithymia scale (TAS) were used for the evaluation of premorbid personality. Psychopathological structure was assessed with SCL-90. The correlation between premorbid personality and current structure of psychopathological states was studied.

OADD patients were characterized by higher scores of frustration tolerance, rigidity and isolation tendency and less expression of neuroticism, esoteric tendencies and motivation compared with ED. In the AND patients, the values of neuroticism and motivation predominated compared with OADD, while the value of frustration tolerance was higher in OADD. A correlation analysis revealed the strong positive relationships of alexithymia, neuroticism and isolation tendency with depression, anxiety, somatization, obsessions and sensitivity in AND group.

The comparison of correlations between OADD and ED revealed no significant differences. It implies the similarity in the pathogenesis of OADD and ED.