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Minimally invasive surgery versus sternotomy in native mitral valve endocarditis: a matched comparison
Markus Kofler1, Karel M Van Praet1,2, Julie Schambach1
1Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany.
Objectives:
The present study compared the clinical outcomes between minimally invasive surgery (MIS) and median sternotomy (MS) in patients with native mitral valve infective endocarditis.
Methods:
From 2009 to 2019, a total of 154 patients with acute (n = 131, 85%) or subacute (n = 23, 15%) native mitral valve infective endocarditis were included in the study. One-to-one nearest neighbour propensity score matching considering endocarditis severity using the dedicated De Feo score and 19 other clinically relevant baseline variables resulted in a population of 39 matched pairs. The matched cohort was investigated regarding operative and postoperative outcomes.
Results:
Both groups showed similar results regarding cardiopulmonary bypass time [MIS: 96 min (77-138), MS: 99 min (88-127); P = 0.780] and aortic cross-clamp time [MIS: 64 min (54-90), MS: 65 min (59-83); P = 0.563], whereas overall operative time was shorter through minimally invasive access [MIS: 138 min (112-196), MS: 187 min (175-230); P = 0.005]. Although the rate of revision for bleeding was similar in both groups [MIS: 12.8% (n = 5), MS: 10.3% (n = 4); P = 1.000], MIS was associated with fewer red blood cell unit transfusions [MIS: 1 unit (0-4), MS: 4 units (2-10); P = 0.001] and fewer fresh frozen plasma unit transfusions [MIS: 0 units (0-0), MS: 1 unit (0-5); P = 0.002]. MIS was associated with a shorter ventilation time [MIS: 708 min (429-1236), MS: 1440 min (659-4411); P = 0.024] and a lower rate of reintubation after extubation [MIS: 5.1% (n = 2), MS: 25.6% (n = 10); P = 0.021].
Conclusions:
In patients suffering from native mitral valve infective endocarditis, MIS provides significant clinical benefits over sternotomy in selected patients.
Subject Collection:
117, 121.
Insights
Minimally invasive surgery (MIS) offers significant clinical benefits over median sternotomy (MS) for native mitral valve infective endocarditis. MIS is associated with shorter operative times and reduced need for blood transfusions.
Area of Science:
- Cardiovascular Surgery
- Infective Endocarditis
- Minimally Invasive Techniques
Background:
- Native mitral valve infective endocarditis poses significant clinical challenges.
- Surgical intervention is often necessary for effective treatment.
- Traditional median sternotomy (MS) carries potential risks and complications.
Purpose of the Study:
- To compare the clinical outcomes of minimally invasive surgery (MIS) versus median sternotomy (MS) in patients with native mitral valve infective endocarditis.
- To evaluate the efficacy and safety of MIS in this patient population.
- To identify potential benefits of MIS over traditional sternotomy.
Main Methods:
- A retrospective study included 154 patients with native mitral valve infective endocarditis (2009-2019).
- One-to-one nearest neighbour propensity score matching was used, considering endocarditis severity (De Feo score) and 19 other variables, resulting in 39 matched pairs.
- Operative and postoperative outcomes were compared between the MIS and MS groups.
Main Results:
- Minimally invasive surgery (MIS) was associated with significantly shorter overall operative times compared to median sternotomy (MS) (P=0.005).
- MIS required fewer red blood cell (P=0.001) and fresh frozen plasma (P=0.002) transfusions.
- Patients undergoing MIS experienced shorter ventilation times (P=0.024) and a lower rate of reintubation (P=0.021).
Conclusions:
- Minimally invasive surgery (MIS) provides significant clinical benefits for selected patients with native mitral valve infective endocarditis.
- MIS may lead to improved postoperative recovery and reduced resource utilization compared to MS.
- Further research may explore long-term outcomes and expand patient selection criteria for MIS.
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