Related Experiment Video
Updated: Jun 25, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
How to Effectively Decrease Patient Co-Payments of High-Cost Drugs Through Innovation: Lessons From the Karmanos
Erlene K Seymour1, Lucius Daniel2, Eva Pointer3
1Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, MI.
Karmanos Specialty Pharmacy automated financial assistance (FA) applications, reducing patient cancer drug costs by 81%. This process significantly lowered out-of-pocket expenses for patients requiring high-cost medications.
Area of Science:
- Oncology Pharmacy Practice
- Health Services Research
- Health Economics
Background:
- High-cost cancer drugs present significant financial challenges for patients.
- Specialty pharmacies play a crucial role in managing medication access and affordability.
- Automating financial assistance processes can alleviate patient financial burdens.
Purpose of the Study:
- To evaluate the impact of an automated financial assistance (FA) application process developed by Karmanos Specialty Pharmacy (KSP).
- To assess the reduction in patient and payer costs associated with high-cost cancer drugs.
- To analyze the types and sources of financial assistance obtained.
Main Methods:
- Observational, retrospective study utilizing KSP claims data from January to December 2019.
- Analysis of drug costs, financial assistance (FA) amounts, and types of FA across different insurance payers (Medicare, private, Medicaid).
- Subset analysis to determine prescription drug delivery times.
Main Results:
- Approximately $10 million in drug claims for Medicare patients, $3.4 million for privately insured, and $3.7 million for Medicaid patients.
- 27% of patients required additional FA, with obtained assistance reducing total patient costs by 81%.
- Foundation grants were the primary source of FA, particularly for Medicare patients, with a median prescription delivery time of under 7 days.
Conclusions:
- An automated FA application process significantly reduced patient out-of-pocket costs for high-cost cancer drugs.
- The KSP process, enhanced by additional pharmacy assistants, proved effective in securing financial aid.
- Efficient FA processes are vital for improving access to and affordability of cancer medications.
Related Concept Videos
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Patient-centered Care
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic illness...
Dosage Regimen: Individualization
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Drug Therapy
Antianxiety Medications

