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Body Composition of Infants With Congenital Gastroschisis

Kera McNelis1,2, Anne Poindexter2, Gillian Goddard3,4

  • 1Division of Neonatology, Cincinnati Children's Hospital Medical Center.

Journal of Pediatric Gastroenterology and Nutrition
|August 18, 2021
PubMed

Insights

Infants with gastroschisis often experience growth issues. This study examined body composition in 10 such infants, finding that fat-free mass is crucial for understanding their growth and development.

Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery
  • Growth and Development

Background:

  • Congenital gastroschisis frequently leads to intrauterine growth restriction and postnatal growth failure in infants.
  • Body composition analysis offers a more comprehensive assessment of infant growth than traditional metrics like weight and length.
  • Fat-free mass (FFM) deposition is linked to better neurodevelopmental outcomes in preterm infants without gastroschisis.

Purpose of the Study:

  • To describe the body composition of infants diagnosed with congenital gastroschisis.
  • To investigate the deposition of fat-free mass (FFM) in infants with gastroschisis.

Main Methods:

  • A case series methodology was employed.
  • The study included a cohort of 10 infants diagnosed with congenital gastroschisis.
  • Body composition was analyzed to assess growth parameters.

Main Results:

  • Limited literature currently exists on the body composition of infants with gastroschisis.
  • This case series provides initial data on the body composition of this specific infant population.
  • Findings highlight the importance of assessing FFM in infants with gastroschisis.

Conclusions:

  • Infants with gastroschisis face significant growth challenges.
  • Body composition, particularly FFM, is a critical indicator for assessing growth and potential developmental outcomes in infants with gastroschisis.
  • Further research is warranted to understand the long-term implications of body composition in gastroschisis survivors.

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