Related Experiment Videos
Cyclic tetrapeptides with sequences related to HC toxin. Conformations and cation binding
1Laboratory of Polyphasic System Physicochemistry--UA 330, Montpellier, France.
International Journal of Peptide and Protein Research
|December 1, 1987
Abstract:
Peptides with sequences related to HC toxin (cyclo(LAla-DAla-L-Aoe-DPro] can adopt a conformation locked by three gamma turns. A "structure--spectroscopy characteristics" relationship is proposed. These peptides can complex Mg++ cations and the binding is accompanied by a transconformation of the peptide backbone. The relevance with the biological activity of the toxin is discussed.