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Related Concept Videos

Hypersensitivities01:30

Hypersensitivities

2.1K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
2.1K
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

72
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
72
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

154
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
154
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

306
Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
306
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

57
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
57
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

49
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
49

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Related Experiment Video

Updated: Oct 23, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

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Some Perspectives on Hypersensitivity to Coronary Stents.

Valentin Chioncel1, Catalina Liliana Andrei1, Radu Brezeanu1

  • 1Department of Cardio-Thoracic Pathology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, 050474, Romania.

International Journal of General Medicine
|August 19, 2021
PubMed
Summary

Allergic reactions to coronary stents are more common than previously thought. Careful patient selection for stent implantation can help reduce complications like restenosis and thrombosis.

Keywords:
Kounis syndromeallergyrestenosisstentsthrombosis

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Area of Science:

  • Cardiology
  • Allergy and Immunology
  • Biomaterials Science

Background:

  • Coronary stents have transformed cardiovascular disease treatment.
  • Despite benefits, stents present limitations, including potential allergic reactions.
  • Patients receive foreign materials in direct contact with the coronary intima.

Purpose of the Study:

  • To highlight the underrecognized issue of allergic reactions to coronary stents.
  • To discuss the contributing factors and clinical manifestations of these reactions.
  • To emphasize the importance of patient selection in mitigating stent-related complications.

Main Methods:

  • Literature review on stent-related hypersensitivity.
  • Analysis of clinical presentations and complications.
  • Discussion of diagnostic challenges and management strategies.

Main Results:

  • Allergic reactions to coronary stents are more frequent than acknowledged.
  • Hypersensitivity can stem from stent components, post-insertion drugs, and environmental factors.
  • Key complications include in-stent restenosis and stent thrombosis.

Conclusions:

  • Allergic reactions to coronary and peripheral stents warrant clinical consideration.
  • Identifying and managing hypersensitivity is crucial for patient outcomes.
  • Pre-procedural assessment of allergy propensity may reduce adverse events.