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Related Experiment Video

Updated: Jun 29, 2026

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
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Post-acute COVID-19 functional movement disorder.

Alpana Garg1, Sachin Goyal2, Alejandro P Comellas3

  • 1Department of Internal Medicine, The University of Iowa, Iowa City, IA, USA.

SAGE Open Medical Case Reports
|August 19, 2021
PubMed
Summary
This summary is machine-generated.

A rare functional movement disorder, characterized by repetitive head flexion, emerged two months after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. This case underscores the potential for long-term neuropsychiatric sequelae following COVID-19.

Keywords:
COVID-19functional movement disorderfunctional neurological disorderlong-term effects of COVID-19neurological manifestationspost-acute sequalae of severe acute respiratory syndrome coronavirus-2

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Psychiatry

Background:

  • Neurological manifestations of COVID-19 are diverse, with movement disorders being relatively uncommon.
  • Persistent debilitating symptoms post-COVID-19 infection require further investigation.

Observation:

  • A 54-year-old male developed repetitive head flexion movements two months after SARS-CoV-2 infection.
  • Initial work-up, including neurological exams and tests, revealed no organic cause.
  • Patient reported severe anxiety and depression, alongside other persistent symptoms like cognitive impairment and fatigue.

Findings:

  • The patient's condition was diagnosed as a functional movement disorder, linked to an underlying neuropsychiatric condition.
  • Despite extensive investigations, no definitive organic pathology was identified.
  • Symptoms persisted at one-year follow-up, significantly impacting quality of life.

Implications:

  • Functional movement disorders can be a manifestation of post-COVID-19 neuropsychiatric sequelae.
  • This case highlights the significant symptom burden and unmet needs of patients with long-term COVID-19 symptoms.
  • Further research is needed to understand and manage these complex post-infectious neurological and psychiatric conditions.