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Updated: Oct 23, 2025

An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
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Perioperative Intravenous Lidocaine and Metastatic Cancer Recurrence - A Narrative Review

Thomas P Wall1,2, Donal J Buggy1,2,3

  • 1Department of Anaesthesiology, Mater Misericordiae University Hospital, School of Medicine, University College Dublin, Dublin, Ireland.

Frontiers in Oncology
|August 19, 2021
PubMed
Summary

Perioperative lidocaine may inhibit cancer cell activity and reduce recurrence risk. Further clinical trials are needed to confirm the anti-cancer benefits of this safe and inexpensive anesthetic agent.

Keywords:
anaesthesiacancerlidocainelocal anaestheticsrecurrencesurgery

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