Fluid intake and urinary osmolality in pediatric patients with functional constipation

Sabine Nunes Boilesen1, Francine C Dias1, Soraia Tahan1

  • 1Division of Pediatric Gastroenterology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781-12 Andar, São Paulo, SP, 04039-032, Brazil.

Insights

Pediatric patients with functional constipation exhibit lower fluid intake and higher urinary osmolality compared to healthy children. This suggests dehydration may play a role in pediatric functional constipation.

Area of Science:

  • Pediatric Gastroenterology
  • Urology
  • Nutrition Science

Background:

  • Functional constipation is a common pediatric condition.
  • Adequate fluid intake is crucial for bowel regularity.
  • Urinary osmolality serves as an indicator of hydration status.

Purpose of the Study:

  • To investigate fluid intake patterns in children with functional constipation.
  • To assess urinary osmolality as a marker of hydration in pediatric functional constipation.
  • To compare hydration status between children with and without functional constipation.

Main Methods:

  • A cross-sectional, case-control study involving 36 children with functional constipation and 93 controls.
  • Fluid intake assessed via daily diet inquiry and 24-hour recall.
  • Hypohydration defined by urinary osmolality > 800 mOsm/kg H2O.

Main Results:

  • Children with functional constipation had significantly lower total water intake (median 1566 mL vs. 2177 mL).
  • Urinary osmolality was significantly higher in the functional constipation group (median 859 mOsm/kg H2O vs. 775 mOsm/kg H2O).
  • A trend towards increased hypohydration was observed in the functional constipation group (OR 2.06, p=0.073).

Conclusions:

  • Pediatric patients with functional constipation demonstrate reduced fluid consumption.
  • Elevated urinary osmolality in constipated children suggests a state of relative dehydration.
  • These findings highlight the potential impact of hydration status on pediatric functional constipation.
Abstract

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