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Fluid intake and urinary osmolality in pediatric patients with functional constipation
Sabine Nunes Boilesen1, Francine C Dias1, Soraia Tahan1
1Division of Pediatric Gastroenterology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 781-12 Andar, São Paulo, SP, 04039-032, Brazil.
Insights
Pediatric patients with functional constipation exhibit lower fluid intake and higher urinary osmolality compared to healthy children. This suggests dehydration may play a role in pediatric functional constipation.
Area of Science:
- Pediatric Gastroenterology
- Urology
- Nutrition Science
Background:
- Functional constipation is a common pediatric condition.
- Adequate fluid intake is crucial for bowel regularity.
- Urinary osmolality serves as an indicator of hydration status.
Purpose of the Study:
- To investigate fluid intake patterns in children with functional constipation.
- To assess urinary osmolality as a marker of hydration in pediatric functional constipation.
- To compare hydration status between children with and without functional constipation.
Main Methods:
- A cross-sectional, case-control study involving 36 children with functional constipation and 93 controls.
- Fluid intake assessed via daily diet inquiry and 24-hour recall.
- Hypohydration defined by urinary osmolality > 800 mOsm/kg H2O.
Main Results:
- Children with functional constipation had significantly lower total water intake (median 1566 mL vs. 2177 mL).
- Urinary osmolality was significantly higher in the functional constipation group (median 859 mOsm/kg H2O vs. 775 mOsm/kg H2O).
- A trend towards increased hypohydration was observed in the functional constipation group (OR 2.06, p=0.073).
Conclusions:
- Pediatric patients with functional constipation demonstrate reduced fluid consumption.
- Elevated urinary osmolality in constipated children suggests a state of relative dehydration.
- These findings highlight the potential impact of hydration status on pediatric functional constipation.
Purpose:
This study aimed to evaluate fluid intake and urinary osmolality in pediatric patients with functional constipation.
Methods:
This was a cross-sectional, case-control study that prospectively included two groups: 36 pediatric patients older than 4 years with functional constipation (Rome III criteria) who were consecutively admitted in a public tertiary pediatric gastroenterology outpatient clinic and 93 controls with normal bowel habits. The control group was recruited from a public school and did not have any of the characteristics of the Rome III criteria. Fluid and food intakes were assessed using a daily diet inquiry and 24 h recording method. Hypohydration was defined as osmolality greater than 800 mOsm/kg H2O in a spot urine sample.
Results:
The age of the functional constipation group (median, 8.9 years; range 7.3-10.0 years) and the control group (8.8 years) was similar (p = 0.51). The proportion of boys in the functional constipation group (76.6%; 25/36) was higher (p = 0.01) than that in the control group (45.2%; 41/93). The total water intake of the functional constipation group (median 1566 mL) was lower (p < 0.001) than that of the control group (median 2177 mL). Urinary osmolality was higher (p = 0.039) in the functional constipation group (median 859 mOsm/kg H2O) than in the control group (median 775 mOsm/kg H2O). The association between hypohydration and functional constipation did not reach statistical significance (Odds ratio 2.06; 95% confidence interval 0.93-4.55; p = 0.073).
Conclusion:
Compared to the control group, patients with functional constipation have lower fluid intake and higher urinary osmolality.
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