Including the environment in models for genetic segregation
Related Experiment Video
Updated: Oct 1, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
Published on: August 24, 2013
1Department of Human Genetics, Medical College of Virginia, Richmond 23298.
Abstract:
Current models for linkage and segregation analysis do not allow for many of the different ways in which the environment may affect risk for a psychiatric disorder. A variety of mechanisms for the contribution of the environment and the correlation and interaction of environment effects with genetic differences are described. The approach to including these effects in models for segregation and linkage is outlined.
Related Concept Videos
Law of Segregation
Law of Independent Assortment
Chromosomal Theory of Inheritance
Law of Independent Assortment
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Gene-Environment Interactions

