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Anatomical variations of the circle of Willis in children

Serdar Solak1, Fethi Emre Ustabasioglu2, Aykut Alkan2

  • 1Department of Radiology, Trakya University School of Medicine, 22030, Edirne, Turkey. serdarsolak@gmail.com.

Pediatric Radiology
|August 19, 2021
PubMed

Insights

The circle of Willis shows varying completion rates in children, with the highest in toddlers and preschoolers. Pediatric Circle of Willis morphology is similar to adults, evolving with age.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Vascular Neurology

Background:

  • The morphology of the Circle of Willis in adults is well-documented.
  • Pediatric Circle of Willis morphology remains under-researched.

Purpose of the Study:

  • Establish reference data for pediatric Circle of Willis morphology and variations.
  • Evaluate temporal evolution and compare pediatric vs. adult Circle of Willis populations.

Main Methods:

  • Retrospective analysis of 273 MR angiograms from 263 pediatric patients (1-215 months).
  • Assessed Circle of Willis vessel completion and variation frequency by age and gender.

Main Results:

  • A 56.1% Circle of Willis completion rate was observed in the pediatric cohort.
  • Completion rates were highest in toddlers/preschoolers (significantly) and lowest in newborns/infants (40%).

Conclusions:

  • Pediatric Circle of Willis completion rates and variations resemble adult patterns.
  • Completion rates increase in toddler/preschooler age groups and decrease in older children.
Abstract

Keywords:
AdolescentsChildrenCircle of WillisMagnetic resonance angiographyNormal variants

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